Fmoc-Gly-OH 29022-11-3 Partners, long-termCooperation

Product Overview

Fmoc-Gly-OH (Fmoc-Glycine) is a high-purity amino acid derivative for solid-phase peptide synthesis, giving researchers and pharmaceutical manufacturers a reliable building block that reduces coupling failures and simplifies purification.

Key Benefits

Purity ≥99% (HPLC) with free amine ≤0.1% – ensures higher coupling yields and fewer impurities, cutting down purification time by minimizing side products.
Batch-to-batch consistency verified by COA – reduces process variability, making scale-up from R&D to production more predictable and cost-effective.
Flexible supply quantities from 25 g to 1 kg or more – supports both early-stage experiments and commercial manufacturing without changing sourcing workflows.
Reliable delivery schedules and responsive technical support – minimizes downtime and facilitates long-term procurement partnerships.
Compatible with standard Fmoc chemistry protocols – no special handling or adaptation required, lowering adoption costs in existing synthesis lines.

Specifications

Parameter	Value	Remarks
Chemical Name	Fmoc-Gly-OH (Fmoc-Glycine)	Also known as N-Fmoc-glycine
CAS Number	29022-11-3	Use for regulatory or ordering verification
Molecular Formula	C₁₇H₁₅NO₄	Calculated
Molecular Weight	297.31 g/mol	Monoisotopic mass: 297.100
Appearance	White to off-white crystalline powder	Visual inspection
Purity	≥99% (HPLC)	Area normalization method
Free Amine Content	≤0.1%	Indicator for deprotection completeness
Melting Point	175°C (decomposition)	Measured by DSC
Storage Temperature	2–8°C	Store in a tightly sealed, light-protected container
Solubility	Soluble in DMF, DMSO, THF; practically insoluble in water	Prepare fresh stock solutions in DMF for SPPS

Applications

Peptide drug discovery – medicinal chemists use this compound to synthesize candidate peptide analogs with reproducible yields in high-throughput screening.
Solid-phase peptide synthesis (SPPS) – provides a dependable Fmoc-protected glycine for routine coupling cycles on automated synthesizers, reducing cycle failures.
Custom peptide production – contract manufacturing organizations rely on its low free-amine content to meet strict purity requirements for clinical-grade peptides.
Protein engineering research – enables incorporation of glycine residues into designed proteins through native chemical ligation and related techniques.
Academic teaching laboratories – offers a stable, low-hazard amino acid derivative for hands-on organic chemistry and biochemistry experiments.

FAQ

What is the purity of Fmoc-Gly-OH?
The purity is ≥99% by HPLC, with ≤0.1% free amine, ensuring minimal by-products and reliable coupling in peptide synthesis.

How should Fmoc-Gly-OH be stored?
Store at 2–8°C in a tightly sealed container, protected from light and moisture, to maintain stability for at least 24 months.

Does Fmoc-Gly-OH dissolve in water?
It is practically insoluble in water. Dissolve it in DMF, DMSO, or THF for peptide synthesis applications.

What is the CAS number of Fmoc-Gly-OH?
The CAS number is 29022-11-3. Use this identifier to verify regulatory documentation or request samples from suppliers.

Are batch analysis reports available?
Yes, each batch is tested by HPLC and a certificate of analysis (COA) is provided with shipment.

What packaging sizes do you offer?
Standard packaging includes glass bottles of 25 g, 100 g, and 500 g, and aluminum foil bags for 1 kg or larger. Custom sizes are available on request.

Can Fmoc-Gly-OH be used in automated peptide synthesizers?
Yes, it is compatible with standard Fmoc chemistry and performs well in automated SPPS instruments without additional method adjustments.

Why Choose This Product

Unlike generic amino acid derivatives, this product offers verified purity and batch-to-batch consistency that directly reduce costly re-runs and purification steps. The supplier, Baishixing, has established a record of stable supply and responsive communication, making it a practical choice for laboratories and contract manufacturers that need long-term cooperation. For teams that prioritize reproducible results and reliable sourcing, this Fmoc-Gly-OH delivers comparable performance to higher-priced alternatives without compromising quality or delivery timelines.