High quality Fmoc-Gly-OH Supplier From China

1. Definition

Fmoc-Gly-OH (CAS 29022-11-3) is a high-purity Fmoc-protected glycine derivative supplied by Baishixing, designed for solid-phase peptide synthesis (SPPS) and similar applications that require consistent batch purity, low racemization, and reliable supply.

2. Core Selling Points

Purity ≥99% (HPLC) – Ensures efficient coupling without extra purification, reducing cost and time in peptide assembly.
Moisture content ≤0.5% (Karl Fischer) – Prevents hydrolysis and guarantees accurate weighing for stoichiometric synthesis.
Annual production capacity of 50 metric tons – Supports both laboratory-scale orders and commercial manufacturing without lead-time fluctuations.
Flexible packaging (25 g to 25 kg) – All vessels are argon-purged and sealed, preserving stability under extended storage.
Full quality documentation – Each batch includes HPLC, NMR, and Karl Fischer test reports; CoA provided with every order.

3. Detailed Parameter Table

Parameter	Value	Additional Notes
Product Name	Fmoc-Gly-OH	Also known as Fmoc-glycine
CAS Number	29022-11-3	Verified identity
Molecular Formula	C₁₇H₁₅NO₄	Calculated based on structure
Molecular Weight	297.31 g/mol	Monoisotopic mass 297.100
Appearance	White to off-white powder	Visual inspection per batch
Purity (HPLC)	≥99.0%	Area normalization method
Water Content (Karl Fischer)	≤0.5%	Measured on each batch
Melting Point	174–177 °C (decomposition)	Literature value; confirmed by DSC
Solubility	Soluble in DMF, DMSO, DCM	Typical for peptide synthesis building blocks
Storage Condition	2–8 °C, sealed, dry place	Keep away from light and moisture
Packaging	25 g / 100 g / 1 kg / 5 kg / 25 kg	Custom sizes available on request
Lead Time	In-stock for 25–100 g; 5–7 working days for bulk orders	For international shipping, add transit time

4. Application Scenarios

Laboratory-scale SPPS: Researchers building custom peptides in academic labs use Fmoc-Gly-OH as the first amino acid to ensure clean coupling on resin.
Pharmaceutical development: Medicinal chemists preparing peptide drug candidates rely on consistent purity to minimize side products in final compounds.
Commercial peptide manufacturing: Production teams in cGMP facilities use this grade for multi-kilogram batches where reproducible quality is mandatory.
Peptide library synthesis: For high-throughput methods, the low moisture content prevents resin swelling variability and improves reproducibility.
Microwave-assisted peptide synthesizers: The compound’s high purity allows rapid coupling cycles without additional recrystallization steps.

5. Common FAQs

What is the shelf life of Fmoc-Gly-OH?Store unopened at 2–8 °C away from moisture. Under these conditions, the product remains stable for at least 2 years. After opening, use within 6 months and reseal under inert gas.

Do you provide a certificate of analysis (CoA) for each batch?Yes. Each shipment includes a CoA with results for HPLC purity, water content, identity (NMR/IR), and appearance. Additional documents such as MSDS and TDS can be sent electronically.

What is the minimum order quantity for a test sample?The minimum order for Fmoc-Gly-OH is 25 grams. This allows you to evaluate the product’s performance in your synthesis before scaling up.

How do you ship the product to maintain stability?For international orders, the powder is packed in sealed aluminium bags with argon gas. Ambient shipping is standard; refrigerated shipping is available upon request for hot climates.

Can you support regulatory submissions like DMF filing?Yes. We can provide the necessary data and reference documents to support Drug Master File (DMF) submissions, including stability studies and raw material specifications.

Are there any impurities that could affect coupling efficiency?The guaranteed HPLC purity of ≥99.0% limits typical impurities such as Fmoc-Gly-Gly and Fmoc-β-alanine to less than 0.1% each. This reduces by-product formation during peptide chain assembly.

What is your typical delivery time for a 1 kg order?A 1 kg order is currently in stock and can be dispatched within 3 working days after confirmation. For orders above 25 kg, allow 5–7 working days for production and quality testing.

6. Differentiation Summary

Baishixing’s Fmoc-Gly-OH provides a price-performance profile that sets it apart from many Chinese suppliers: instead of minimizing cost by accepting lower purity, we maintain ≥99% HPLC purity and package under argon—most competitors offer only ≥98% with nitrogen flushing. Our integrated raw material supply and 50-ton annual capacity allow us to keep prices competitive while delivering full analytical data per batch. This product is best suited for peptide manufacturers and research teams that need reproducible SPPS results, complete documentation, and the ability to scale from grams to tons without changing vendors.