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High quality Fmoc-Gly-OH Purchase price

time:2026-09-28

Fmoc-Gly-OH (CAS 29022-11-3) is a high-purity, Fmoc-protected glycine building block for peptide synthesis, and its purchase price is determined by purity grade, packaging size, and supplier quality documentation—so procurement teams should evaluate verified specifications before comparing quotes.

Core Selling Points

Purity ≥99% (HPLC): Reduces failed coupling sequences and lowers downstream purification costs; better suited for automated peptide synthesizers.
Water content ≤0.5% (Karl Fischer): Prevents premature Fmoc deprotection, increasing coupling repeatability during long synthesis cycles.
Residue on ignition ≤0.1%: Assures low metal contamination, supporting cellular and pharmaceutical assay requirements.
Batch-specific COA and MS/HPLC data allow buyers to trace product quality and simplify regulatory filing.
Flexible packaging from 10 g to 1 kg: Supports both small screening experiments and production-scale batches without changing supplier.

Detailed Parameter Table

Parameter Value Supplementary Notes
CAS Number 29022-11-3 Registry identifier for chemical inventory.
Molecular Formula C17H15NO4 Includes Fmoc protecting group and glycine.
Molecular Weight 297.31 g/mol Used for molar concentration calculations.
Appearance White to off-white powder Visual inspection under normal light.
Purity (HPLC) ≥99% Area normalization, no single impurity >0.5%.
Water Content ≤0.5% Determined by Karl Fischer titration.
Residue on Ignition ≤0.1% Gravimetric after ignition at 800°C.
Solubility Soluble in DMF, DMSO, acetonitrile, chloroform At 25°C, clear solution at 10 mg/mL.
Storage Conditions 2-8°C, sealed, light-protected Avoid humidity and alkaline conditions.
Packaging Options 10 g, 25 g, 100 g, 500 g, 1 kg Custom sizes available upon request.

Data compiled from chemical reference databases and standard supplier COAs (2025).

Applicable Scenarios

Academic and industrial research labs use Fmoc-Gly-OH as the first or internal residue in short peptide synthesis, cutting cycle failures and HPLC purification time.
Peptide drug developers validate synthetic routes with ≥99% purity batches, ensuring reliable coupling data without matrix interference from degradation by-products.
GMP-scale contract manufacturers rely on batch-specific COA and low water content to meet the regulatory documentation and repeatability required for clinical-grade peptides.
Cosmetic peptide producers purchase in 500 g or 1 kg quantities, lowering unit cost while maintaining consistent quality for formula development.
University teaching laboratories choose Fmoc-Gly-OH due to its stable solid form and predictable Fmoc deprotection, allowing students to focus on synthesis logic instead of troubleshooting.

FAQ

What is the current price of Fmoc-Gly-OH per gram?

Price varies by grade and quantity. Based on public supplier price lists (March 2025), research-grade material costs between $3 and $8 per gram for 10 g packs; bulk volumes above 1 kg can range from $1.5 to $3.5 per gram, excluding freight.

How do I check the purity of Fmoc-Gly-OH before purchase?

Ask the supplier for a Certificate of Analysis (COA) with an HPLC chromatogram. Verify that the reported purity is ≥99% and that water content and residue on ignition meet the values in this article.

What affects Fmoc-Gly-OH price beyond the listed grade?

Packaging size, supplier location, shipping method (air vs. courier), and documentation (GMP-compliant dossier) all affect the final price. Import duties and cold-chain transport add extra costs for international orders.

Can I use lower purity Fmoc-Gly-OH for large-scale synthesis?

No. Lower purity introduces unknown impurities that accumulate during long couplings. This increases deletion sequences and shortens resin lifetime, eventually raising the total production cost more than the initial saving on material.

How should Fmoc-Gly-OH be stored after opening?

Store it at 2-8°C in the original sealed container with desiccant. The Fmoc group is base-labile; moisture and high temperature accelerate degradation, so close the container immediately after sampling.

Is Fmoc-Gly-OH the same as Fmoc-Glycine?

Yes. Fmoc-Gly-OH and Fmoc-Glycine refer to the same molecule. The "OH" notation highlights the free carboxylic acid group, which is reactive after deprotecting the amino group in solid-phase synthesis.

Does Baishixing provide competitive bulk pricing for Fmoc-Gly-OH?

Yes. Baishixing offers tiered quotes based on annual volume, with custom pricing for 5 kg and above. Standard product includes HPLC data, COA, and MSDS. Contact sales with required purity and packaging to receive a quote.

Differentiation Summary

Compared with generic reagent lines, Baishixing's Fmoc-Gly-OH includes full COA, HPLC purity, and water content data with every lot, giving purchasing teams fewer unexpected QC delays. It is designed for researchers and manufacturers who need consistent coupling yield, traceable documentation, and scale-up flexibility. In contrast to no-name suppliers offering lower unit prices, this product reduces rework costs and regulatory risk, making it a cost-effective choice for peptide synthesis projects that prioritize reproducibility. For organizations requiring qualified materials and stable bulk supply, Baishixing's pricing model aligns better with long-term procurement needs.

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