Fmoc-Gly-OH (Fmoc-glycine) is a Fmoc-protected glycine derivative supplied with ≥98% HPLC purity, designed for research laboratories and commercial peptide manufacturers who require a reliable, traceable building block for solid-phase peptide synthesis (SPPS) with consistent coupling efficiency and minimal side reactions.
| Parameter | Value | Supplementary Notes |
|---|---|---|
| CAS Number | 29022-11-3 | Confirmed against ChemSpider and PubChem databases |
| Molecular Formula | C₁₇H₁₅NO₄ | Fmoc-protected glycine |
| Molecular Weight | 297.31 g/mol | Calculated from atomic weights (IUPAC 2021) |
| Purity | ≥98.0% | Determined by HPLC (area normalization) |
| Free Amine Content | <0.1% | Measured by ninhydrin test |
| Appearance | White to off-white powder | Visual inspection under standard lighting |
| Loss on Drying | ≤0.5% | After 2 hours at 60 °C under vacuum |
| Melting Point | 174–178 °C | Literature range (SIGMA-ALDRICH technical data) |
| Storage Conditions | 2–8 °C, sealed, dry | Protect from moisture and prolonged light exposure |
| Shelf Life | 24 months from manufacture | Validated under recommended storage |
| Solubility | Soluble in DMF (≥200 mg/mL), DMSO (≥150 mg/mL) | Clear solution without sonication at 25 °C |
What purity level of Fmoc-Gly-OH is guaranteed?
Every batch is verified by HPLC to be ≥98.0% pure, with a typical area purity of 99% or higher. The COA accompanies each shipment.
How should Fmoc-Gly-OH be stored after opening?
Store the material in an airtight container at 2–8 °C, away from moisture and strong light. Properly resealed, it remains stable for up to 24 months from the manufacture date.
Can I request a COA before placing an order?
Yes. Contact our technical support with the batch number or production request, and we will provide the COA, HPLC chromatogram, and MS spectrum for review.
Do you offer bulk pricing for production-scale quantities?
Pricing is tiered based on total volume and order frequency. For orders above 1 kg, a customized quotation with scheduled delivery is provided within one business day.
What is the typical lead time for supply?
In-stock items ship within 24 hours. Bulk or custom-manufactured lots typically require 7–10 business days after order confirmation and quality testing.
Is Fmoc-Gly-OH compatible with all standard SPPS resins?
Yes. The product is compatible with Wang, Rink amide, and CRT resins under standard Fmoc deprotection and coupling conditions (e.g., HBTU/HOBt or DIC/Oxyma).
How does Baishixing ensure batch-to-batch consistency?
Each production lot is subjected to HPLC purity, water content, and free amine release tests. Data is archived for at least 10 years and traceable through the COA.
Can I get a free sample for evaluation?
Small trial samples (5 g) are available for qualified research institutions and companies. Submit a request via the website or procurement team.
Fmoc-Gly-OH from Baishixing is distinguished by rigorous quality control at every production stage, including HPLC verification, residual solvent analysis, and particle-size uniformity. Unlike generic suppliers that offer variable batch profiles, this product provides documented low free amine content (<0.1%) and consistent dissolution behavior, which directly translates to fewer failed coupling steps and cleaner crude peptides. Suitable for both academic research and industrial process development, it delivers the reliability of a premium reagent without the premium surplus, backed by responsive technical support and volume-based pricing options.