Fmoc-Gly-OH Export Price

Fmoc-Gly-OH (CAS 29022-11-3) is an Fmoc-protected glycine derivative used as a building block in solid-phase peptide synthesis, giving pharmaceutical R&D labs and research institutions a reliable amino acid input whose per-gram cost depends primarily on purity grade, order quantity, and supplier type.

Core Selling Points

Purity ≥98% (HPLC, area % at 220 nm): Each batch ships with a Certificate of Analysis containing the full chromatogram, so incoming QC can release the material without duplicating analytical work—cutting raw-material testing time by 2–3 days per lot.
Melting point 174–178°C: A narrow melting range signals high crystallinity and consistent lot-to-lot quality, which translates into reproducible coupling yields when using standard HBTU/DIPEA activation in Fmoc-SPPS.
Bulk-tier pricing at 500 g and above: Volume discounts bring the per-gram cost down to roughly $2.0–$2.5 at 1 kg scale, approximately 30–40% below the per-gram list price for 25 g research packs.
24-month shelf life at 2–8°C: Stability studies across multiple production lots show no significant impurity growth during the stated shelf life, allowing labs to stock inventory without waste.
Full documentation with every order: HPLC, mass spectrometry, ¹H-NMR, residual solvent data, and a lot-specific COA are provided as PDFs, simplifying regulatory review for GMP-adjacent workflows.

Detailed Specification Table

Parameter	Value	Supplementary Notes
Product Name	Fmoc-Gly-OH (Fmoc-Glycine)	N-(9-Fluorenylmethoxycarbonyl)glycine
CAS Number	29022-11-3	PubChem CID: 70699816
Molecular Formula	C₁₇H₁₅NO₄	Verified by high-resolution mass spectrometry per batch
Molecular Weight	297.31 g/mol	Monoisotopic mass: 297.1001 Da
Purity	≥98.0%	Reverse-phase HPLC, area normalization at 220 nm
Appearance	White to off-white crystalline powder	Visual inspection per internal SOP; no visible contamination
Melting Point	174–178°C	Differential scanning calorimetry, 10°C/min heating rate
Loss on Drying	≤0.5%	Gravimetric analysis: 3 h at 60°C under vacuum
Solubility	≥100 mg/mL in DMF	Clear solution at 25°C without heating
Residual Solvents	Within ICH Q3C limits	GC headspace analysis, lot-specific report included
D-Enantiomer Content	≤0.1%	Chiral derivatization followed by GC analysis
Storage Condition	2–8°C, sealed, light-protected	Do not freeze; keep desiccant inside the container
Shelf Life	24 months from manufacturing date	Accelerated stability data on request
Packaging Options	10 g, 25 g, 100 g, 500 g, 1 kg, 5 kg, 25 kg	Laminated aluminum bags under argon; fiber drums for bulk

Application Scenarios

Academic peptide labs synthesizing 5–20 residue peptides for antibody generation or structure-function studies can use this building block in standard Fmoc-SPPS cycles, expecting complete coupling with a 3-fold reagent excess.
Pharmaceutical discovery departments running SAR (structure-activity relationship) studies on peptide analogs benefit from the consistently low D-enantiomer content, which keeps impurity profiles comparable across parallel synthesis arms.
CROs and CDMOs producing custom peptides for preclinical research use the included COA and analytical traces to populate batch records, reducing documentation lead time before final product release.
Diagnostic reagent manufacturers coating ELISA plates or preparing peptide-hapten conjugates find the sub-$3.0 per gram price at 100 g scale attractive for production economics.
Biotech startups with modest research budgets can purchase verified ≥98% purity material without paying catalog premium pricing, freeing capital for other consumables.

Frequently Asked Questions

How much does Fmoc-Gly-OH cost per gram in 2025?

Indicative pricing from supplier quotations: 25 g packs list between $3.0 and $6.0 per gram from catalog distributors; direct manufacturers quote $1.5–$3.5 per gram at equal purity, with notable price reductions for standing orders.

Where can I find the lowest Fmoc-Gly-OH price?

Direct chemical manufacturers in China and India offer the lowest base quotes, often 20–40% below American and European catalog resellers. Include shipping, customs clearance, and minimum order quantity in the per-gram calculation.

Does Fmoc-Gly-OH purity affect peptide synthesis yield?

Yes. At ≥98% purity, standard couplings proceed normally for peptides up to 30 residues. Below 98%, deletion sequences and truncation by-products become conspicuous, especially in long syntheses or when using automated synthesizers.

What is the standard packaging for Fmoc-Gly-OH?

Packaging ranges from 10 g foil bags for laboratory use to 25 kg fiber drums for production. Intermediate sizes of 100 g and 500 g are the most frequently ordered, balancing handling convenience with volume and shipping cost efficiency.

What lead time should I expect for Fmoc-Gly-OH deliveries?

Stocked items (≤1 kg) ship within 24–48 hours. Orders between 5 kg and 25 kg typically require 10–15 business days for synthesis, QC release, and packing, plus shipping time to destination.

Are analytical documents included with each Fmoc-Gly-OH order?

Each shipment includes a lot-specific Certificate of Analysis listing HPLC purity, melting point, loss on drying, and residual solvent results. NMR and MS spectra are available on request within 48 hours.

Does Fmoc-Gly-OH require cold-chain shipping?

Short-distance shipments can tolerate ambient temperature if delivery completes within 5 days, but international freight should use insulated packaging with cold packs. Temperature data loggers are recommended and available as an optional service.

Can I request a custom purity grade above 98%?

Yes, ≥99% and ≥99.5% grades are manufactured on request. The recrystallization step adds 3–5 business days and increases unit pricing by 20–50%, depending on quantity.

How Fmoc-Gly-OH Compares with Other Market Sources

Large catalog suppliers such as MilliporeSigma and Chem-Impex list Fmoc-Gly-OH at $4.0–$8.0 per gram for research sizes, with pricing that reflects supply chain overhead rather than production cost. Low-cost marketplace listings on platforms like eBay and Alibaba frequently lack batch-level documentation, making incoming QC mandatory and risking synthesis failures that cost more in wasted reagents than the material savings. Baishixing supplies this compound directly from its production facility with batch-tested HPLC purity, complete analytical files, and volume-structured pricing that lands between these two extremes—typically $2.0–$3.5 per gram at research scale and below $2.0 at production volumes. That combination of documented quality and manufacturer-direct pricing makes particular sense for academic labs, startup biotechs, and contract manufacturers who need reproducible synthesis without absorbing the margins of multi-tier distribution.