Fmoc-Gly-OH 29022-11-3

Fmoc-Gly-OH (Fmoc-glycine) is a high-purity amino acid derivative supplied by Baishixing, designed for researchers and pharmaceutical manufacturers who require a reliable Fmoc-protected glycine building block with low impurity levels for solid-phase peptide synthesis.

Core Selling Points

Purity ≥98.5% (HPLC): Ensures consistent coupling efficiency in peptide chain assembly, reducing failed synthesis cycles.
Free amino content ≤0.1%: Minimizes undesired side reactions during deprotection, improving final product purity.
Moisture content ≤0.5%: Guarantees stable storage and accurate weighing for solution preparation.
Batch-to-batch consistency: Every batch is tested with a Certificate of Analysis (COA), allowing reproducible results across experiments.
Custom packaging options: Available from 100 g to 25 kg, supporting both research and commercial-scale production without repackaging costs.

Technical Specifications

Parameter	Value	Notes
Product Name	Fmoc-Gly-OH	Fmoc-glycine
CAS Number	29022-11-3	Confirmed by CAS registry
Molecular Formula	C17H15NO4
Molecular Weight	297.31 g/mol
Appearance	White to off-white powder	Visual inspection
Purity (HPLC)	≥98.5%	Area percent method
Loss on Drying	≤0.5%	3 hours at 60°C
Free Amino Content	≤0.1%	UV-Vis assay
Solubility	Soluble in DMF, DMSO, THF	Clear solution at 10% w/v
Storage Conditions	2-8°C, keep dry, avoid light	Stable for 24 months
Packaging	100g, 500g, 1kg, 5kg, 25kg	Custom available

Typical Use Cases

Solid-phase peptide synthesis: Researchers use Fmoc-Gly-OH as a standard building block to introduce glycine into peptide chains with high efficiency.
Pharmaceutical intermediate manufacturing: Contract manufacturing organizations (CMOs) rely on its consistent purity for producing GLP-1 receptor agonists and other peptide-based drugs.
Biochemical research: Academic labs studying enzyme-substrate interactions use this compound to synthesize modified peptides for binding assays.
Diagnostic reagent development: In vitro diagnostic companies utilize Fmoc-Gly-OH to prepare peptide antigens with controlled epitope sequences.
Custom peptide services: Peptide suppliers use this material to fulfill orders for custom sequences requiring glycine at specific positions.

Frequently Asked Questions

Q: What is the CAS number of Fmoc-Gly-OH?
A: The CAS number is 29022-11-3, which uniquely identifies this compound in chemical databases.

Q: How is the purity of Fmoc-Gly-OH determined?
A: Purity is measured by HPLC using area normalization, with a minimum acceptance criterion of 98.5%.

Q: Does the supplier provide a Certificate of Analysis for each batch?
A: Yes, every batch ships with a COA detailing purity, moisture, free amino content, and other test results.

Q: What is the shelf life of Fmoc-Gly-OH?
A: When stored at 2-8°C in a sealed container protected from light, the shelf life is 24 months.

Q: Can I request a sample before placing a bulk order?
A: Free samples are available for qualified research institutions; shipping fees may apply.

Q: What is the minimum order quantity for commercial quantities?
A: The standard MOQ is 1 kg for standard grades, but lower quantities can be supplied for research use.

Q: Is this product suitable for GMP manufacturing?
A: Yes, we offer a GMP-grade version with additional documentation and tighter specifications upon request.

Q: What payment and shipping terms are available?
A: We support T/T, L/C, and PayPal for payment, and ship via DHL, FedEx, or sea freight depending on order size.

Why It Stands Out

Unlike many suppliers that offer Fmoc-Gly-OH with purity around 98%, Baishixing ensures a strict 98.5% minimum through reverse-phase HPLC testing. The product also features lower free amino and moisture content, which directly impacts synthesis yield and minimizes purification burden. Additionally, flexible packaging from research to production scale, along with full documentation including COA and MSDS, makes it a dependable choice for research institutions and pharma/biotech companies seeking a traceable supply for peptide development.