Baishixing Co.,Ltd  
 
PRODUCT

Fmoc-Gly-OH 29022-11-3 Factory

time:2026-10-27

Overview

Fmoc-Gly-OH (N-fluorenylmethoxycarbonyl-glycine) is a high-purity amino acid derivative produced by Baishixing for peptide synthesis, providing consistent quality for research and pharmaceutical manufacturing.

Key Selling Points

Purity ≥99.0% (HPLC) – Minimizes racemization and side reactions in solid-phase peptide synthesis, improving final peptide yield.
Free glycine content ≤0.5% – Reduces by-product formation during coupling steps, ensuring reliable peptide purity.
Batch-to-batch consistency – Each batch is tested against validated reference standards; a certificate of analysis is included with every shipment.
Loss on drying ≤0.5% – Prevents premature Fmoc deprotection, extending shelf life under recommended storage conditions.
Flexible packaging – Glass bottles from 10 g to 500 g, with custom bulk packaging available.

Detailed Specifications

Parameter Value Additional Notes
CAS Number 29022-11-3 Identified as Fmoc-glycine
Molecular Formula C17H15NO4 Confirmed by mass spectrometry
Molecular Weight 297.31 g/mol Calculated
Appearance White to off-white crystalline powder Visual inspection
Purity (HPLC) ≥99.0% Area normalization method
Free Glycine ≤0.5% HPLC method
Loss on Drying ≤0.5% Dried at 60°C under vacuum
Melting Point 170°C – 175°C Decomposition point
Solubility Soluble in DMF, DMSO, dichloromethane Not readily soluble in water
Storage 2°C – 8°C, sealed, dry, and protected from light Stability verified for 24 months
Packaging 10 g, 25 g, 100 g, 500 g glass bottle Custom packaging upon request

All analytical data are measured per batch and reported in the certificate of analysis (COA) delivered with each shipment.

Applicable Scenarios

Solid-Phase Peptide Synthesis (SPPS) – Used as a building block for introducing glycine at any position; high purity reduces deletion sequences.
Pharmaceutical R&D – Suitable for process development when documented batch data and a consistent impurity profile are required.
Custom peptide production – Enables reproducible manufacturing of peptide APIs and intermediates.
Academic research – Provides reliable coupling efficiency for biochemistry and drug discovery laboratories.
Process scale-up – Bulk packaging and consistent quality support the transfer from laboratory synthesis to pilot production.

FAQ

What is Fmoc-Gly-OH used for?

Fmoc-Gly-OH is a protected amino acid derivative used as a monomer in solid-phase peptide synthesis. It supplies a glycine residue with an Fmoc protecting group on the nitrogen, allowing controlled deprotection during chain assembly. Its high purity ensures minimal side reactions, yielding clean peptides for research and development applications.

What purity does Fmoc-Gly-OH have?

The standard product is analyzed by HPLC and shows a purity of ≥99.0%. A certificate of analysis is provided with each batch, listing purity, free glycine content, loss on drying, appearance, and melting point. This strict control supports reproducible peptide synthesis and helps avoid sequence deletions or racemization by-products.

How should Fmoc-Gly-OH be stored?

Store Fmoc-Gly-OH at 2°C to 8°C in an airtight container away from light and moisture. Keep the bottle tightly sealed after each use and avoid condensation inside. Under these conditions, the product remains stable for 24 months from the manufacturing date, as verified by stability testing.

Is Fmoc-Gly-OH soluble in water?

Fmoc-Gly-OH has very low solubility in water. It dissolves well in polar aprotic solvents such as DMF, DMSO, and dichloromethane. For peptide coupling, prepare solutions in DMF or NMP at the desired concentration. Avoid aqueous conditions unless using a co-solvent or adjusted pH for specific applications.

Can I get a certificate of analysis?

Yes, each shipment includes a certificate of analysis with the batch number, manufacturing date, expiry date, and measured values for all test items. The COA provides full traceability and is suitable for quality audits and regulatory filings in pharmaceutical and research settings.

Does Fmoc-Gly-OH require special handling?

Wear nitrile gloves, safety glasses, and a lab coat. Use a fume hood or local exhaust to avoid inhaling fine particles. Handle under dry conditions because moisture can cause partial Fmoc deprotection. After opening, flush the container with inert gas and reseal it immediately.

What is the typical lead time?

For standard glass bottle packs from 10 g to 500 g, the lead time is 5 to 7 business days after order confirmation. For custom bulk quantities or non-standard packaging, lead time depends on production schedule and will be confirmed by our sales team. Rush orders may be arranged.

Differentiation and Suitable Users

This Fmoc-Gly-OH is manufactured with a focus on low impurities and strict analytical control, setting it apart from commodity-grade reagents that may vary in quality between batches. The documented specifications, including HPLC purity, free glycine content, and loss on drying, give researchers and production teams a reliable basis for process validation. It is best suited for scientists and production engineers who require consistent starting materials for peptide synthesis, especially when regulatory documentation and reproducible results are critical. The manufacturer Baishixing supports both small-scale research and larger production requirements with flexible packaging and responsive technical service.

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