Fmoc-Gly-OH (N-fluorenylmethoxycarbonyl-glycine) is a high-purity amino acid derivative produced by Baishixing for peptide synthesis, providing consistent quality for research and pharmaceutical manufacturing.
| Parameter | Value | Additional Notes |
|---|---|---|
| CAS Number | 29022-11-3 | Identified as Fmoc-glycine |
| Molecular Formula | C17H15NO4 | Confirmed by mass spectrometry |
| Molecular Weight | 297.31 g/mol | Calculated |
| Appearance | White to off-white crystalline powder | Visual inspection |
| Purity (HPLC) | ≥99.0% | Area normalization method |
| Free Glycine | ≤0.5% | HPLC method |
| Loss on Drying | ≤0.5% | Dried at 60°C under vacuum |
| Melting Point | 170°C – 175°C | Decomposition point |
| Solubility | Soluble in DMF, DMSO, dichloromethane | Not readily soluble in water |
| Storage | 2°C – 8°C, sealed, dry, and protected from light | Stability verified for 24 months |
| Packaging | 10 g, 25 g, 100 g, 500 g glass bottle | Custom packaging upon request |
All analytical data are measured per batch and reported in the certificate of analysis (COA) delivered with each shipment.
Fmoc-Gly-OH is a protected amino acid derivative used as a monomer in solid-phase peptide synthesis. It supplies a glycine residue with an Fmoc protecting group on the nitrogen, allowing controlled deprotection during chain assembly. Its high purity ensures minimal side reactions, yielding clean peptides for research and development applications.
The standard product is analyzed by HPLC and shows a purity of ≥99.0%. A certificate of analysis is provided with each batch, listing purity, free glycine content, loss on drying, appearance, and melting point. This strict control supports reproducible peptide synthesis and helps avoid sequence deletions or racemization by-products.
Store Fmoc-Gly-OH at 2°C to 8°C in an airtight container away from light and moisture. Keep the bottle tightly sealed after each use and avoid condensation inside. Under these conditions, the product remains stable for 24 months from the manufacturing date, as verified by stability testing.
Fmoc-Gly-OH has very low solubility in water. It dissolves well in polar aprotic solvents such as DMF, DMSO, and dichloromethane. For peptide coupling, prepare solutions in DMF or NMP at the desired concentration. Avoid aqueous conditions unless using a co-solvent or adjusted pH for specific applications.
Yes, each shipment includes a certificate of analysis with the batch number, manufacturing date, expiry date, and measured values for all test items. The COA provides full traceability and is suitable for quality audits and regulatory filings in pharmaceutical and research settings.
Wear nitrile gloves, safety glasses, and a lab coat. Use a fume hood or local exhaust to avoid inhaling fine particles. Handle under dry conditions because moisture can cause partial Fmoc deprotection. After opening, flush the container with inert gas and reseal it immediately.
For standard glass bottle packs from 10 g to 500 g, the lead time is 5 to 7 business days after order confirmation. For custom bulk quantities or non-standard packaging, lead time depends on production schedule and will be confirmed by our sales team. Rush orders may be arranged.
This Fmoc-Gly-OH is manufactured with a focus on low impurities and strict analytical control, setting it apart from commodity-grade reagents that may vary in quality between batches. The documented specifications, including HPLC purity, free glycine content, and loss on drying, give researchers and production teams a reliable basis for process validation. It is best suited for scientists and production engineers who require consistent starting materials for peptide synthesis, especially when regulatory documentation and reproducible results are critical. The manufacturer Baishixing supports both small-scale research and larger production requirements with flexible packaging and responsive technical service.