Fmoc-Gly-OH 29022-11-3 Factory From China

1. Product Definition

Fmoc-Gly-OH (Fmoc-glycine) is a high-purity protected amino acid supplied by Baishixing for solid-phase peptide synthesis, enabling researchers and manufacturers to achieve efficient coupling with minimal side reactions and reliable batch reproducibility.

2. Key Selling Points

≥99% HPLC purity – Ensures accurate stoichiometric loading during peptide chain assembly, reducing the need for downstream purification.
Low free glycine (≤0.1%) – Prevents premature chain termination and competing acylation, improving overall peptide yield.
Batch-to-batch consistency – Each lot is tested for identity, purity, and impurity profile per COA, making synthesis results reproducible across scales.
Flexible packaging – Available in 25 g, 100 g, 500 g and 1 kg packs, supporting both R&D experiments and production batches.

3. Technical Specifications

Parameter	Value	Remarks
Product Name	Fmoc-Gly-OH	Fmoc-glycine protected amino acid
CAS No.	29022-11-3	–
Molecular Formula	C17H15NO4	–
Molecular Weight	297.31 g/mol	–
Appearance	White to off-white crystalline powder	Visual inspection
Purity (HPLC)	≥99.0%	Area percent
Melting Point	174–176 °C	Decomposition at higher temperature
Loss on Drying	≤0.5%	Drying at 105 °C for 3 hours
Residue on Ignition	≤0.1%	Per Ph. Eur. 2.4.14
Heavy Metals	≤20 ppm	Per Ph. Eur. 2.4.8
Solubility	Soluble in DMF, DCM, THF	Insoluble in water
Storage	2–8 °C	Keep tightly sealed, protected from light
Package Sizes	25 g, 100 g, 500 g, 1 kg	Custom sizes available

Source: Supplier's technical datasheet; a batch-specific Certificate of Analysis (COA) is provided with each shipment.

4. Suitable Applications

Academic research – Chemistry and biochemistry labs using Fmoc solid-phase synthesis can use this reagent to produce peptide antigens and protein fragments with consistent results.
Pharmaceutical development – Drug discovery teams synthesizing peptide-based leads benefit from low impurity levels that simplify toxicity and pharmacokinetic profiling.
Contract manufacturing – Peptide CMOs and CDMOs can scale up production from milligrams to kilograms while maintaining regulatory documentation through batch-specific COAs.
Peptide libraries – High-throughput screening groups that synthesize combinatorial peptide libraries rely on the lot-to-lot consistency to avoid false positives.

5. Common Questions

Q1: What is the CAS number of Fmoc-Gly-OH?
Fmoc-Gly-OH has the CAS registry number 29022-11-3. This unique identifier is widely used in chemical databases, ordering systems and regulatory filings. It also helps your team to cross-check product identity when comparing offers from different suppliers, avoiding misprocurement errors. The number is printed on every certificate of analysis issued by the manufacturer.

Q2: How pure is the Fmoc-Gly-OH from this supplier?
It has a minimum purity of 99.0% as measured by high-performance liquid chromatography (HPLC). The exact area percentage and each known impurity are reported in the batch-specific Certificate of Analysis. This transparency allows you to verify the material before use and maintain documentation for GMP or research audits.

Q3: Is Fmoc-Gly-OH stable at room temperature?
Fmoc-Gly-OH may be kept at room temperature for a few hours during weighing, but long-term storage must be at 2–8 °C in a tightly sealed container protected from light and moisture. Following these conditions, the product remains stable for at least two years from the date of manufacture according to the supplier’s stability study.

Q4: Can Fmoc-Gly-OH be dissolved in water?
No, Fmoc-Gly-OH is practically insoluble in water. For peptide coupling, dissolve it in anhydrous DMF, DCM, or THF. If a solution appears cloudy, filter it through a 0.45 µm PTFE membrane before adding to the reaction mixture to prevent blocking automated fluid lines.

Q5: Do you offer samples for evaluation?
Yes, qualified researchers can request a free 5 g sample. Send the supplier an inquiry including your institution, application, and expected monthly consumption. The sample batch will be shipped with a full COA, so you can perform your own HPLC and coupling tests before committing to a larger purchase.

Q6: What is the lead time for a 1 kg order?
Standard production and quality release require 5 working days for a 1 kg order, excluding transit time. For urgent projects, express courier delivery such as DHL or FedEx can shorten shipping to 3–5 business days, depending on the destination. Larger or custom-packed orders are planned after confirmation.

Q7: Does this product perform well in automated peptide synthesizers?
Yes, it is compatible with common automated peptide synthesizers because the powder is free-flowing and free of lumps. Each Certificate of Analysis includes particle size distribution and bulk density data, so you can confirm the material will feed consistently in powder dispersion systems. We recommend storing the bottle under dry conditions before loading the synthesizer to avoid moisture-related aggregation.

6. Differentiation Summary

Compared with standard Fmoc-Gly-OH from other regions, this product offers a distinctive combination of tight impurity control and cost efficiency, driven by vertically integrated manufacturing. It is especially valuable for peptide manufacturers who need reproducible quality at scale, as well as for academic groups that require consistent reagent performance without budget overruns. For buyers evaluating long-term procurement, this Chinese-origin product balances quality documentation, availability, and price.