Fmoc-Gly-OH is a high-purity (≥99%) Fmoc-protected glycine derivative used as a core building block in solid-phase peptide synthesis, designed for researchers and pharmaceutical developers who need reproducible, low-impurity reagents for efficient peptide assembly.
| Parameter | Value | Supplementary Note |
|---|---|---|
| Product Name | Fmoc-Gly-OH (Fmoc-glycine) | CAS 29022-11-3 |
| Molecular Formula | C₁₇H₁₅NO₄ | Exact mass: 297.10 g/mol |
| Molecular Weight | 297.31 g/mol | Standard molar mass for calculations |
| Purity | ≥99.0% | Determined by HPLC area normalization |
| Appearance | White to off-white powder | Visual inspection per lot |
| Melting Point | 174–178 °C | Matches literature range (uncorrected) |
| Solubility | Soluble in DMF, DMSO, and THF | Prepare fresh before use in coupling reactions |
| Residual Solvents | <0.1% | Per residual solvent analysis |
| Storage Conditions | 2–8 °C, dry, protected from light | Stable for 24 months if stored unopened |
| Shelf Life | 24 months | Re-test date provided per batch |
| Packaging | 25 g, 100 g, 500 g, 1 kg | Sealed under inert gas with desiccant |
What is Fmoc-Gly-OH used for?
It is used as a protected glycine monomer in peptide synthesis, where the Fmoc group protects the amino terminus and is removed under mild basic conditions.
Is Fmoc-Gly-OH soluble in DMF?
Yes, it is readily soluble in DMF at concentrations up to 1 M, making it suitable for standard automated peptide synthesizers.
How should I store Fmoc-Gly-OH?
Store at 2–8 °C in a dry, airtight container protected from light. Avoid exposure to moisture and strong bases.
What is the purity of Baishixing's Fmoc-Gly-OH?
Every batch is tested with HPLC and provides ≥99% purity. The certificate of analysis includes chromatograms and residual solvent data.
Can Fmoc-Gly-OH be used in Boc-based synthesis?
This product is specifically Fmoc-protected. For Boc synthesis, you would need Boc-Gly-OH instead; Fmoc chemistry requires different deprotection conditions.
Does the product come with a certificate of analysis?
Yes, a COA is supplied with each shipment, detailing purity, melting point, and residual solvent results per batch.
What is the shelf life of Fmoc-Gly-OH?
The shelf life is 24 months from the date of manufacture when stored under recommended conditions.
Compared to generic amino acid suppliers, Baishixing's Fmoc-Gly-OH offers a more balanced combination of high HPLC purity, strict residual solvent control, and flexible packaging sizes. This makes it especially suited for researchers and production teams who need consistent quality for method development, GMP-oriented studies, or scaled-up peptide manufacturing without negotiating premium specialty-chemical prices. For laboratories that prioritize reproducibility and documentation reliability over low-cost alternatives, this reagent provides a dependable foundation.
