1. Basic Information
Product Name: Fmoc-Gly-OH
Aliases:Fmoc-Glycine;FMOC-L-Glycine;Fluorenylmethoxycarbonyl-Glycine;N-Fluorenylmethoxycarbonyl-Glycine; A-Aminopentanedioic acid; N-(9-Fluorenylmethoxycarbonyl)-Glycine
CAS Number: 29022-11-5
Molecular Formula: C17H15NO4
Molecular Weight: 297.305 (or 297.31)
EINECS Number: 249-373-3
2. Physical Properties
Appearance: White solid or powder
Density: 1.3±0.1 g/cm³
Boiling Point: 545.7±33.0 °C at 760 mmHg
Melting Point: 174~175 °C (lit.)
Flash Point: 283.8±25.4 °C
Vapor Pressure: 0.0±1.5 mmHg at 25°C
Refractive Index: 1.620
3. Chemical Properties
Stability: Does not decompose if used and stored as specified. No known hazardous reactions have been reported, but oxidizing agents should be avoided.
Solubility: Specific solubility data is not provided.
4. Synthesis Method
Fmoc-Gly-OH is typically prepared via organic synthesis. A common synthetic route involves the reaction of glycine with Fmoc-Cl (9-fluorenylmethoxycarbonyl chloride).
5. Applications
Biomedical Field: Fmoc-Gly-OH is an important research tool in the biomedical field and is used in the synthesis of peptide compounds, such as polypeptide drugs and biomarkers. Its protective group can be easily removed under mild alkaline conditions, making the synthesis process convenient.
Biochemistry and Clinical Research: Used in amino acid infusions and the synthesis of pharmaceuticals, it can be applied in the treatment of liver diseases and heart conditions.
Other Uses: It is also used as a biochemical reagent, an intermediate in organic synthesis, and a metal chelating agent. Additionally, it can be used in cosmetics.
6. Storage and Transportation
Storage Conditions: Should be sealed and stored at 2 ºC~8 ºC.
Transportation Methods: Logistics, road transport, EMS, SF Express, etc., can all be used. Specific arrangements depend on the supplier and customer requirements.
Fmoc-Gly-OH is a chemical substance with wide-ranging applications, playing an important role in the fields of biomedicine, biochemical reagents, and organic synthesis.
