Fmoc-Gly-OH (Fmoc-glycine) is a Fmoc-protected glycine derivative for solid-phase peptide synthesis (SPPS), providing research and commercial-scale production with a consistent, high-purity amino acid building block.
| Parameter | Value | Additional Notes |
|---|---|---|
| Product name | Fmoc-Gly-OH | Also known as Fmoc-glycine, N-α-Fmoc-glycine |
| CAS number | 29022-11-3 | Unique identifier for regulatory and ordering purposes |
| Molecular formula | C₁₇H₁₅NO₄ | Confirmed by mass spectrometry and NMR |
| Molecular weight | 297.31 g/mol | Calculated from molecular formula |
| Appearance | White to off-white crystalline powder | Visual inspection conforms to standard |
| Purity (HPLC) | ≥99.0% (area percentage) | Method: C18 reverse-phase column, UV detection at 254 nm |
| Melting point | 174–176 °C | Differential scanning calorimetry (DSC) |
| Loss on drying | ≤0.5% | Measured after 3 h at 105 °C |
| Solubility | Soluble in DMF, DMSO, acetonitrile | Prepare fresh; avoid prolonged storage in solution |
| Storage conditions | Store at 2–8 °C, keep container tightly closed | Protect from light and moisture |
| Shelf life | 36 months from manufacturing date when stored as recommended | Confirmed by stability studies |
| Packaging | 25 g, 100 g, 500 g, 1 kg, 5 kg, 10 kg | Custom packaging available upon request |
| Regulatory document | Certificate of Analysis (CoA) provided with each batch | Additional documents on request |
Is Fmoc-Gly-OH compatible with standard Fmoc solid-phase peptide synthesis?
Yes, it is fully compatible. The Fmoc group is removed by piperidine, and the carboxylic acid is activated by standard coupling reagents like HATU or DIC.
What is the storage temperature for Fmoc-Gly-OH?
Store at 2–8 °C, in a tightly closed container protected from light and moisture. Under these conditions, the shelf life is 36 months.
Can you supply Fmoc-Gly-OH in custom packaging for large-scale production?
Yes. We offer flexible packaging from 25 g to 10 kg, and custom container sizes can be arranged based on your annual usage forecast.
How do you ensure batch-to-batch consistency?
Each batch is tested by HPLC, including impurity profile and chiral purity confirmation. The Certificate of Analysis documents all results, and average control limits are tighter than specification.
Does Baishixing provide regulatory documentation for this product?
We provide a standard Certificate of Analysis and can supply additional documents such as the material safety data sheet (MSDS), structural characterization data, and stability summary on request.
What is the typical lead time for Fmoc-Gly-OH?
For standard packaging (25 g to 1 kg), lead time is 7–10 working days after order confirmation. For bulk orders (>5 kg), lead time is 3–4 weeks, depending on production schedule.
What is the racemization level of Fmoc-Gly-OH?
The D-isomer content is below 0.1%, as determined by chiral HPLC, ensuring minimal racemization during activation and coupling.
Fmoc-Gly-OH is a commodity in peptide building blocks, yet the value of a reliable supplier is often underestimated. While many vendors offer similar catalogue prices, Baishixing provides a combination of low racemization, strict lot release, and flexible capacity that directly addresses the pain points of repeat production: inconsistent purity, missing documentation, and supply interruptions. The product is routinely used by R&D groups who need a dependable foundation for method development and by procurement teams who value contractual pricing security. For organizations seeking a long-term manufacturer—not just a spot-volume source—this Fmoc-Gly-OH offering balances technical performance with commercial predictability.
