Baishixing Co.,Ltd  
 
PRODUCT

Fmoc-Gly-OH 29022-11-3 Price

time:2026-10-13

Fmoc-Gly-OH (N-fluorenylmethoxycarbonyl-glycine) is a protected glycine derivative designed for researchers and pharmaceutical companies performing solid-phase peptide synthesis, providing a reliable building block with 99% minimum purity and consistent batch-to-batch performance.

Key Advantages

Purity ≥ 99% (HPLC): Each batch is tested using high-performance liquid chromatography, ensuring minimal impurities that can interfere with coupling reactions during peptide chain elongation.
Specific rotation [α]²⁰D = 0° to +1.0° (c=5, DMF): This tightly controlled optical rotation range confirms consistent chiral purity for reproducible synthesis outcomes.
Loss on drying ≤ 0.5%: Low residual moisture prevents unwanted side reactions and extends storage stability under recommended conditions (2–8°C, protected from light).
Appearance as white to off-white powder: Visual uniformity is verified across batches, simplifying handling and dissolution in standard solvents such as DMF, DMSO, or NMP.
Supply capacity up to 1,000 kg per month: A steady production scale supports both research-scale (5 g–1 kg) and manufacturing-scale (10–100 kg) needs without supply chain interruption.

Detailed Technical Specifications

Parameter Value Additional Notes
Product name Fmoc-Gly-OH Also known as Fmoc-glycine
CAS number 29022-11-3 Verified against SciFinder registry
Molecular formula C₁₇H₁₅NO₄ Exact mass 297.31 g/mol
Molecular weight 297.31 g/mol Calculated from elemental composition
Purity ≥ 99.0% Determined by HPLC (area normalization)
Melting point 174–178 °C Differential scanning calorimetry (DSC)
Loss on drying ≤ 0.5% Measured after 2 h at 60 °C under vacuum
Residue on ignition ≤ 0.1% Sulfated ash method
Solubility Soluble in DMF, DMSO, NMP Slightly soluble in dichloromethane
Storage condition 2–8 °C, sealed, dry, dark Stable for 24 months under recommended storage
Packaging options 25 g, 100 g, 1 kg, 5 kg, 25 kg Custom packaging available for bulk orders

Recommended Usage Scenarios

Academic peptide research: Graduate students and postdocs working on solid-phase peptide synthesis (SPPS) use Fmoc-Gly-OH to introduce glycine residues at any position with high coupling efficiency.
Custom peptide manufacturing: Contract development and manufacturing organizations (CDMOs) producing peptide APIs rely on this reagent for its consistent quality and large-volume supply capability.
Pharmaceutical R&D: Drug discovery teams developing peptide-based therapeutics need a reliable Fmoc-glycine source for lead optimization and scale-up feasibility studies.
Diagnostic reagent production: Companies manufacturing peptide antigens or enzyme substrates use Fmoc-Gly-OH to construct peptides with high specificity and reproducibility.
Bioconjugation research: Scientists preparing peptide-drug conjugates (PDCs) or antibody-drug conjugates (ADCs) utilize this protected amino acid as a spacer building block with stable coupling performance.

Common Questions

What is the purity of Fmoc-Gly-OH from Baishixing?
Purity is ≥ 99.0% as determined by HPLC. Every batch includes a certificate of analysis with actual chromatogram data.

Does Fmoc-Gly-OH require special storage?
Yes, store at 2–8 °C in a sealed container, protected from light and moisture. Under these conditions, shelf life is 24 months.

What solvents can dissolve Fmoc-Gly-OH?
DMF, DMSO, and NMP dissolve it readily. DMF is preferred for standard SPPS coupling reactions.

Can I get a free sample before purchasing?
Samples are available for qualified researchers and procurement teams. Typically 5–10 g provided at no cost, shipping charges may apply.

What is the lead time for bulk orders (25 kg or more)?
Standard lead time is 10–15 business days after purchase order confirmation. For large quantities, a production schedule is provided upfront.

Is Fmoc-Gly-OH suitable for GMP manufacturing?
Yes, the product is manufactured under controlled processes. GMP documentation, including batch records and validation protocols, is available upon request and audit.

How does Baishixing ensure batch consistency?
Each production batch is tested for purity, optical rotation, moisture, and appearance. Retained samples are kept for two years for traceability.

Why Choose This Fmoc-Gly-OH Over Other Products

Standard Fmoc-Gly-OH reagents on the market often vary in purity (95–98%) and lack full characterization data, which can lead to failed coupling reactions or unpredictable impurities in peptide products. This product from Baishixing provides a minimum purity of 99% with complete HPLC, DSC, and moisture certificates, enabling researchers to avoid unnecessary troubleshooting and re-synthesis costs. Its documented solubility behavior and optical rotation specifications make it straightforward to incorporate into both manual SPPS and automated synthesizers. For research groups and production facilities that require reliable raw materials for regulated applications, this Fmoc-Gly-OH offers an openly verifiable quality profile backed by a manufacturer capable of flexible scaling from gram to metric ton quantities. It is particularly suited for customers who audit suppliers for quality systems, demand full documentation packages, and need stable long-term sourcing relationships.

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Tel:+8602888531548
Whatsapp:+86 18881690597
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