FMOC-Arg(Pbf)-OH (CAS 154445-77-9) Product Introduction
1. Product Overview
FMOC-Arg(Pbf)-OH (CAS 154445-77-9) is a high-purity protected amino acid reagent designed for solid-phase peptide synthesis and biomedical research institutions, solving low purity stability, premature side-chain deprotection and high impurity interference of conventional arginine protected monomers.
2. Core Product Categories
Protected Amino Acid Reagent, Peptide Synthesis Intermediate, Biomedical Fine Chemical Raw Material, Laboratory Organic Synthesis Reagent, Solid-Phase Peptide Monomer
3. Target Crowd
Peptide synthesis processing enterprises, biomedical research laboratories, pharmaceutical R&D institutions, organic chemistry experiment teams and biochemical raw material testing centers
4. Core Solved Pain Points
·Ordinary protected arginine monomers suffer unstable side-chain protection, causing side reactions during peptide chain synthesis
·Low-grade products contain high residual intermediate impurities, reducing the yield and purity of finished peptide products
·Conventional reagents have poor long-term storage stability, leading to monomer degradation and experimental failure
·Generic monomers show inconsistent batch purity, resulting in poor repeatability of synthesis experiments and industrial production
5. Core Selling Points
·Maintains 99.6% minimum HPLC purity with maximum single impurity below 0.10%, effectively reducing side reaction interference in precision peptide synthesis.
·Adopts stable Pbf side-chain protection structure, achieving 99.5% protection rate and avoiding premature deprotection during conventional synthesis conditions.
·Controls moisture content below 0.20% via low-temperature refining technology, preventing monomer hydrolysis and structural failure during sealed storage.
·Retains 99.0% effective monomer activity after 12 months of professional sealed storage, ensuring consistent batch synthesis results.
6. Core Product Parameters
This product has a fixed CAS number of 154445-77-9 with a molecular formula of C28H38N4O7S and molecular weight of 574.69 g/mol. It appears as white crystalline powder at 25°C with 99.6% minimum HPLC purity. The side-chain protection rate reaches 99.5%. Moisture content is controlled below 0.20%. Sealed storage at 2°C to 8°C provides a 12-month valid shelf life with stable chemical properties.
7. Application Scenarios
Peptide synthesis enterprises use this high-stability monomer for solid-phase peptide synthesis to improve finished product purity and production yield.
Biomedical laboratories adopt the protected amino acid reagent for custom polypeptide modification and biomedical molecule research.
Pharmaceutical R&D institutions apply low-impurity monomers for active pharmaceutical peptide ingredient development and experimentation.
Chemical testing laboratories utilize standardized reagents for amino acid monomer component calibration and impurity analysis tests.
8. Frequently Asked Questions
Q1: What is the HPLC purity level of FMOC-Arg(Pbf)-OH CAS 154445-77-9?
This product delivers 99.6% minimum HPLC purity with single impurity below 0.10%, fully meeting high-standard peptide synthesis and laboratory research requirements.
Q2: What advantages does Pbf side-chain protection bring to synthesis experiments?
The stable Pbf protection structure avoids premature deprotection under conventional reaction conditions and significantly reduces synthesis side reactions.
Q3: Will long-term storage cause degradation of this protected amino acid monomer?
Strict low-moisture control and low-temperature sealed storage maintain 99.0% monomer activity without degradation within 12 months.
Q4: What core scenarios is FMOC-Arg(Pbf)-OH mainly used for?
It is widely applied in solid-phase peptide synthesis, custom polypeptide preparation, biomedical research and pharmaceutical peptide raw material development.
Q5: Why is batch stability important for protected amino acid reagents?
Stable batch purity and activity eliminate experimental data deviation and ensure consistent yield in industrial peptide mass production.
Q6: What storage conditions are required for this peptide synthesis monomer?
Sealed and shaded storage at 2°C to 8°C isolates moisture and oxidation to sustain complete chemical structural stability.
