The crystal structure of N6-Cbz-L-lysine is formed by specific molecular arrangements.
Molecular Structure Perspective
The molecular formula of N6-Cbz-L-lysine is C₁₄H₂₀N₂O₄. It is derived from L-lysine, where the ε-amino group (N6) is protected by a benzyloxycarbonyl (Cbz) group. L-lysine itself is a basic amino acid, featuring a carboxyl group (–COOH), an amino group (–NH₂), and a guanidino group (–CH₂–CH₂–CH₂–NH₂). In N6-Cbz-L-lysine, the benzyloxycarbonyl group connects to the nitrogen atom via a carbonyl group, forming an amide bond that protects the ε-amino group.
Intermolecular Interactions in Crystals
Within the crystal, molecules pack through interactions such as hydrogen bonds and van der Waals forces:
Polar groups (e.g., carboxyl and amino groups) form hydrogen bonds with corresponding groups of adjacent molecules, stabilizing the crystal structure.
The benzyl benzene ring may further influence molecular arrangements via π-π stacking interactions.
These interactions enable N6-Cbz-L-lysine molecules to form a regular three-dimensional array, constituting the specific crystal structure. However, precise crystal structure parameters (e.g., unit cell parameters, space group) require determination by experimental methods such as X-ray single-crystal diffraction.
