Baishixing Co.,Ltd  
 
Hydantoin
  • Brand:baishixing
  • Origin:sichuanchengdu
  • Code:00002
  • Price: ¥160/Kg
  • Createtime: 2024-09-09
  • Updatetime: 2024-09-09
Product Details
CAS 461-72-3
PU 99%
MF C3H4N2O2
Hydantoin is an organic compound belonging to a class of heterocyclic compounds. Structurally, it is a five-membered ring containing two nitrogen atoms and three carbon atoms, with a keto group at position 2 and 4. Hydantoin and its derivatives are of significant interest in both pharmaceuticals and industrial applications due to their versatile chemical properties.

Structure and Composition
The chemical formula for hydantoin is C3H4N2O2. The core structure of hydantoin features a heterocyclic ring, which contains both nitrogen and oxygen. The basic hydantoin structure can be chemically modified to produce various derivatives, which enhances its usefulness in different fields.

Biological and Pharmaceutical Applications
Hydantoin derivatives have been widely explored for their medicinal properties. Some of the most well-known hydantoin-based drugs include:

Phenytoin: A commonly used antiepileptic drug that helps control seizures by stabilizing neuronal membranes and reducing abnormal electrical activity in the brain.
Fosphenytoin: A water-soluble prodrug of phenytoin used for the treatment of epilepsy, particularly in emergency situations such as status epilepticus.
Dantrolene: A muscle relaxant used to treat conditions like spasticity and malignant hyperthermia by acting on muscle cells to reduce calcium release and prevent prolonged muscle contraction.
Industrial Applications
Hydantoin derivatives are also useful in industrial and cosmetic applications:

Biocides: Halogenated hydantoins, such as bromochlorohydantoins, are widely used as disinfectants and biocides in water treatment processes (e.g., swimming pools) because of their ability to release active halogen compounds slowly, providing long-term antimicrobial effects.
Cosmetics and Skincare: Hydantoin derivatives like imidazolidinyl urea and diazolidinyl urea are used as preservatives in cosmetics and personal care products. They act as antimicrobial agents, helping to extend the shelf life of products by preventing bacterial growth.
Synthesis and Chemistry
Hydantoin can be synthesized through the Bucherer–Bergs reaction, which involves the reaction of an aldehyde with ammonium carbonate and potassium cyanide. The versatility of hydantoin’s structure allows it to undergo a wide range of chemical reactions, making it a valuable building block for synthesizing various pharmaceutical compounds and industrial materials.

Conclusion
Hydantoin is a compound of immense importance due to its broad applications in both pharmaceuticals and industrial sectors. Its derivatives, such as phenytoin and dantrolene, play a critical role in medical treatments, particularly for neurological conditions and muscle disorders. Meanwhile, hydantoin’s usefulness in biocides, water treatment, and cosmetics highlights its industrial significance. This versatile compound continues to be a subject of research and innovation in various scientific fields.
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