Boc-beta-Alanine
- Price: ¥1000/Kg
- Createtime: 2024-09-06
- Updatetime: 2024-09-06
Product Details
CAS |
3303-84-2
|
PU |
99%
|
MF |
C8H15NO4
|
Boc-beta-Alanine (tert-butoxycarbonyl-beta-alanine) is a chemical compound commonly used in organic synthesis, particularly in peptide chemistry. It is a derivative of beta-alanine, a naturally occurring beta-amino acid, with the addition of a tert-butoxycarbonyl (Boc) protecting group. This protecting group is often employed to temporarily block the amino group during chemical reactions, making Boc-beta-alanine a valuable intermediate in peptide and protein synthesis.
Chemical Structure and Properties
Chemical Formula: C8H15NO4
Molecular Weight: 189.21 g/mol
Structure: Boc-beta-alanine consists of a beta-alanine backbone with a tert-butoxycarbonyl group attached to its amine function. The Boc group provides stability during reactions, preventing unwanted side reactions involving the amine.
Applications in Peptide Synthesis
Boc-beta-alanine is widely used in the field of peptide synthesis. The Boc protecting group allows chemists to control the sequence of reactions when assembling peptides. Once the desired peptide chain has been synthesized, the Boc group can be removed under mild acidic conditions, allowing the exposed amine group to participate in further reactions or to complete the peptide structure.
Importance in Research and Development
Due to its versatility, Boc-beta-alanine plays a critical role in the development of pharmaceuticals, biomaterials, and research related to amino acid and peptide functions. By enabling selective protection and deprotection, it simplifies the design of complex molecules.
Conclusion
Boc-beta-alanine is a key intermediate in organic synthesis, especially in peptide production. Its role as a protecting group in organic chemistry is indispensable, facilitating advancements in drug discovery and biochemical research.